脑卒中后抑郁临床研究进展

摘要

脑卒中后抑郁是影响脑卒中患者生存和功能恢复的严重并发症,患病率约30％,多发生于脑卒中1年内,尤其是脑卒中3个月内.其危险因素主要包括脑卒中后病残、脑卒中前抑郁病史、脑卒中严重程度、认知功能障碍和焦虑症状等.治疗方法主要有药物治疗、心理治疗、康复治疗和物理治疗等,其中康复治疗可以显著减少脑卒中后抑郁发生率,改善预后.进一步深入研究脑卒中后抑郁发生机制、优化康复治疗方案,对改善预后具有重要意义.%Post-stroke depression (PSD) is a serious complication affecting the survival and functional recovery of stroke patients.The prevalence rate of PSD is about 30％.PSD happens mostly within one year after stroke,and especially within 3 months after stroke.The main risk factors of PSD were disability,past history of depression,stroke severity,cognitive dysfunction and anxiety symptoms.The treatment principles of PSD include drug treatment,psychological therapy,rehabilitation therapy,physical therapy and others.Especially,rehabilitation therapy can significantly reduce the incidence of PSD and improve the prognosis.Further study on the mechanism of PSD and optimization of PSD rehabilitation therapy can improve PSD prognosis.