Is China a low risk area for dementia?

摘要

Objoctlve: To investigate whether China is a low riak area for dementia, we conducted a prevalence survey in Beijing, China. Participants: A total of 3244 residents aged 55 years and ovcr- from two Distncts and onc county covcring 7 urban and 8 rural communitics was drawn through a stratified multiple stage cluster sampling. Of these, 3094 (95.2%) were interviewed. Design: Using a two-phase procedure, a Chinese version of Mini-Mental State Examination with 3 cut-off scores depending on respondertt's level of education was administered to all participates in 1997 Those who scored below the cutoff points and a subsample of those with scores in the normal range were interviewed in phase 2 to identify those with dementia through a set of diagnostic examination and the DSM-V criteria. A follow-up study conducted in 1998 for all persons who entered in phase 2 to identify those with Alzheimer's dementia ando vascular dcmcntia by thc utilization of N1NCDS-ADRDA, and NINCDS-AIREN critcria and to classify the severity of dementia by GDS criteria. Results: The ovarall prevalence of dementia was 4. 7% in individuals aged 55 years and over, 7.8% in those aged 65 years and over. Tie prevalerce of AD was higher than VD, especially in older age group, 2.6 vs. 1.8%, 1.8 vs. 2.7%, and 11.5 w. 2.9% for individuals aged 55 years and over, 65 years and over and 75 years and over, respectively There was little difference in cruud prevalence in individuals aged 65 years and over between urban and rurai communities (4.2 vs. 5.8% for AD and 1.8 w. 4. 1% for VD). Concluslon: Our overall prevalence is c onsiderably higher than previously reported estimates fiom Chuna and similar to thosc rcpoitcd in whitcs, suggcating that China is not a low risk arca for AD