目的:探讨咀嚼口香糖对Lenke 5型青少年特发性脊柱侧凸(adolescent idiopathic scoliosis,AIS)患者后路融合术后胃肠道功能恢复的影响.方法:2016年1月至2018年1月海军军医大学附属长征医院收治的行后路融合手术的 Lenke 5型AIS患者随机分为口香糖组和对照组(注册号:ChiCTR-IOR-17013449).口香糖组患者术后第1~3天每天8:00、12:00、18:00咀嚼口香糖20~30 min;对照组不给予咀嚼口香糖处理.主要终点指标:术后初次通气时间、初次肠蠕动时间、术后住院时间及进食时间.次要终点指标:术后镇痛药用量、腹部疼痛及恶心评分、术后并发症.结果:最终纳入99例患者,其中口香糖组49例,对照组50例.两组患者术后首次通气时间(P=0.162)、肠蠕动时间(P=0.387)、首次进食时间、术后住院时间(P=0.730)差异均无统计学意义.两组患者术后并发症发生率、镇痛药用量、腹痛及恶心评分差异无统计学意义.结论:Lenke 5型AIS患者后路融合术后咀嚼口香糖不能加速胃肠道功能恢复.%Objective:To evaluate the effect of chewing gum on promoting recovery of bowel function in Lenke 5 adolescent idiopathic scoliosis(AIS)patients undergoing surgical correction.Methods:AIS patients scheduled for posterior spinal fusion surgery at our institution from January 2016 to January 2018 were randomly divided into gum group(chewing gum for 20-30 minutes at 8:00,12:00,and 18:00 on the 1st to the 3rd day after surgery)and control group without chewing gum (ChiCTR-IOR-17013449).The primary endpoints included the time of flatus,the time of peristalsis resuming,the duration of hospital stay,and the time of eating.The secondary endpoints included the postoperative opioid consumption,the scores of pain and nausea and the incidence of complications.Results:Totally 99 patients were included with 49 in gum group and 50 in control group.There were no significant differences in the time of flatus(P= 0.162),time of peristalsis resuming(P=0.387),time of eating and duration of hospital stay(P= 0.730)between groups,the postoperative complications,opioid consumption and postoperative scores of pain and nausea were not significantly different between groups as well.Conclusions:Chewing gum does not hasten the recovery of bowel function after posterior spinal fusion surgery for Lenke 5 adolescent idiopathic scoliosis.
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