Objective To evaluate the sex difference of percutaneous coronary intervention(PCI) among octogenarian patients with acute coronary syndrome (ACS). Methods A total of 80 patients aged 85 years and over with ACS undergoing PCI were enrolled in this study. The in-hospital and one year clinical follow-up outcome including all-cause mortality,major adverse cardiac event( MACE),stroke and other major bleeding were collected and analyzed. Results Of the 80 patients,37(46.3% ) were female and were more likely to have hypertension,single vessel lesion and DES implant while were less likely to have hyperlipidemia and a history of MI ,PCI and three vessel lesion. Female patients had a higher in-hospital MACE rate( 10. 8% vs 7.0% :P>0.05). Also,at one year,female patients had a similar MACE rate(5.7% vs 4.9% ,P =0.10). Conclusions Female aged patients with acute coronary syndrome underwent PCI may be associated with increased in-hospital MACE rate. Incomplete revascularization may be still benefit to this special population.%目的 探讨性别差异对高龄急性冠脉综合征患者经皮冠状动脉介入治疗预后的影响.方法 回顾性分析80例85岁以上急性冠脉综合征患者,观察性别差异对住院期间和长期预后的影响.结果 女性组高血压病、单支病变及DES植入比例略高；而既往心肌梗死史、既往冠脉介入治疗史、血脂异常、三支病变比例低于男性组.住院期间主要心血管不良事件( MACE)发生率要高于男性组(10.8％ vs7.0％;P＞0.05).随访1年时MACE发生率两组相似(5.7％ vs 4.9％；P=0.10).尽管80％患者仅植入1个支架,但1年生存率较高.结论 高龄女性ACS接受PCI住院期间MACE发生率要高于男性,不完全血运重建策略仍可使这一特殊人群长期获益.
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