内毒素、降钙素原在鉴别急性胆管炎及急性胆囊炎中的意义

摘要

Objective To explore the value of serum the significance of endotoxin(ET),procalcitonin(PCT) in the differential diagnosis between acute cholangitis and acute cholecystitis.Methods Sixty-one patients were col-lected,including 20 acute cholangitis,21 acute cholecystitis,10 chronic cholangitis and 10 chronic cholecystitis.Serum ET and PCT were detected in all subjects.Results Serum ET and PCT of patients with acute cholangitis were signifi-cantly higher than the acute cholecystitis(t =4.130,P <0.05).Serum ET and PCT of patients with acute biliary tract infection were significantly higher than the chronic biliary tract infection(t =9.629,t =5.365,P <0.05).Conclusion Joint detection of ET and PCT can increase the early diagnosis rate of acute biliary tract infection.ET and PCT are closely related to the degree of biliary tract infection.%目的：探讨内毒素（ET）、降钙素原（PCT）在鉴别急性胆管炎及急性胆囊炎中的价值。方法检测61例患者血清 ET 及 PCT 浓度，其中急性胆管炎组20例，急性胆囊炎组21例，慢性胆管炎组10例，慢性胆囊炎组10例，比较各组间 ET 及 PCT 的血清学浓度差异。结果急性胆管炎患者血清中 ET、PCT 水平较急性胆囊炎组明显升高（t ＝4．130，P ＜0．05）。急性胆道感染较慢性胆道感染患者 ET、PCT 血清学水平明显升高（t ＝9．629， t ＝5．365，均 P ＜0．05）。结论联合检测患者血清 ET、PCT 浓度可提高急性胆道感染早期确诊率，且 ET、PCT与胆道感染炎症程度密切相关。