高效、可重复使用的多相催化剂SiO_2-NaHSO_4用于水中三组分一锅法合成八氢喹唑啉-2,5-二酮(英文)

摘要

An environmentally benign method for the synthesis of octahydro-quinazolin-2,5-diones by the reaction of aromatic aldehydes,dimedone,and urea in the presence of SiO2-NaHSO4 is reported.SiO2-NaHSO4 acts as an efficient,mild,and recyclable heterogeneous catalyst to give excellent yields within a short reaction time in water at 60-80℃.