视网膜静脉阻塞与高脂血症患者血脂异常对比研究

摘要

目的:探讨眼科视网膜静脉阻塞(RVO)患者与心内科高脂血症患者及健康人群血脂水平的差异.方法:分析2017年6月至2018年1月首诊眼科的RVO患者(35例)与首诊心内科诊断含高脂血症的患者(35例)及健康体检人群(35例)血脂水平的差异.结果: (1)与健康组比较, RVO组和高脂血症组血总胆固醇(TC) 、甘油三酯(TG)水平均显著升高,血高密度脂蛋白—胆固醇(HDL—C)水平均显著降低( P＜0.05或＜0. 01) ,高脂血症组血低密度脂蛋白—胆固醇(LDL—C)水平显著升高(P＝0.001) ; (2)与高脂血症组比较, RVO组患者血TC [ (5.73 ± 0.91) mmol／L比(5. 09 ± 0. 83) mmol／L] 、 TG [ (2. 31 ± 1.37) mmol／L比(1.81 ± 1.89) mmol／L] 、LDL—C [ (3.11 ± 0. 79) mmol／L比(2.55 ± 0. 42) mmol／L]水平均显著降低(P均＜0.01) .结论: RVO患者血脂水平高于健康人,但比心内科高脂血症组的血脂(TC , TG , LDL—C)水平低,说明血脂水平升高是RVO的发病因素,但不是唯一因素, RVO还有其他发病因素,需要探讨.%Objective :To explore difference of blood lipid levels among patients with retinal vein occlusion (RVO) from department of ophthalmology , those with hyperlipidemia from department of cardiology and healthy people .Methods :Blood lipid levels were compared among 35 RVO patients who visited department of ophthalmology for the first time ,35 patients with hyperlipidemia who visited department of cardiology for the first time and 35 healthy people undergoing physi—cal examination from Jun 2017 to Jan 2018. Results : (1) Compared with healthy group ,there were significant rise in blood levels of total cholesterol (TC) and triglyceride (TG) ,and significant reduction in blood level of high density lipoprotein cholesterol (HDL—C) in RVO group and hyperlipidemia group (P＜0.05 or ＜0.01) ,and significant rise in blood level of low density lipoprotein cholesterol (LDL—C) in hyperlipidemia group , P＝ 0.001 ; (2 ) Compared with hyperlipidemia group ,there were significant reductions in levels of TC [ (5.73 ± 0.91) mmol／L vs.(5.09 ± 0.83) mmol／L] ,TG [ (2.31 ± 1.37) mmol／L vs.(1.81 ± 1.89) mmol／L] and LDL—C [ (3.11 ± 0.79) mmol／L vs.(2.55 ± 0.42) mmol／L] in RVO group , P＜0.01 all.Conclusion : Blood lipid levels of RVO patients are significantly higher than those of healthy people , but those were reduced than hyperlipidemia group indicated that blood lipid levels rise is a pathogenic factor ,but not only one ,its other pathogenic factor should be investigate .