To observe effect of ibutilide, a new Ⅲ antiarrhythmic drug, for atrial fibrillation (AF) car-dioversion. Methods: A total of 32 AF patients were randomly divided into ibutilide group (n = 18, received ibutilide 1mg intravenous within 15min, another 1mg was given intravenously after 30min if it was invalid) and amiodarone group (n= 14, received amiodarone 150mg intravenous within 15min, another 150mg was given intravenously after 30min if it was invalid). Cardioversion condition and time were observed in two groups. Results: Cardioversion rate of AF within 90min in ibutilide group was significantly higher than that of amiodarone group (77.8% vs. 28.6%). that within 4h was also significantly higher than that of amiodarone group (100% vs. 71.4%), P<0.01 both. Conclusion- Ibutilide is a drug for safe and effective cardioversion of atiial fibrillation.%目的:观察新型Ⅲ类抗心律失常药物伊布利特转复心房纤颤的疗效.方法:选择32例房颤患者,随机分为两组:伊布利特组(18例),伊布利特1mg,于15min内静注,如无效30 min后再给予1mg静注;胺碘酮组(14例),胺碘酮150mg,于15min内静注,如无效30min后再给予150mg静注.观察两组房颤转复情况及时间.结果:伊布利特组90min内转复房颤率明显高于胺碘酮组(77.8％比28.6％),4h内转复房颤率亦明显高于胺碘酮组(100％比71.4％),P＜0.01.结论:伊布利特是一种转复房颤的快速、安全、有效的药物.
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