多柔比星心肌毒性监测及预防研究的进展

摘要

多柔比星（doxorubicin，DOX）属蒽醌类抗肿瘤抗生素，是目前临床应用最广泛的抗癌药之一，但对心脏有毒性作用，怎样减轻其心脏毒性，仍然是目前研究的热门问题。本文就DOX心脏毒性的监测及预防进行综述。%Doxorubicin (DOX)belongs to anthraquinone anti-tumor antibiotics,which is now one of most widely used anti-cancer drugs in clinic,but it possesses cardiotoxicity.How to reduce its cardiotoxicity is still a hot problem in current research.This article made an overview for monitoring and prevention of DOX cardiotoxicity.