Objective:To observe the therapeutic effect of dual-chamber pacemaker on bradyarrhythmia and analyze its influence on heart function.Methods:A total of 86 patients with bradyarrhythmia undergoing dual-chamber pacemaker implantation were enrolled and followed up for six months.Their clinical symptom scores (evaluated ac-cording Karolinska questionnaire),heart function and improvement of quality of life (QOL)were observed.Re-sults:Compared with before pacemaker implantation,there were significant rise in clinic symptom scores of short breath and acratia [(7.20±5.50)scores vs.(15.00±4.30)scores],dizziness [(3.45±2.20)scores vs.(7.80± 1.40)scores],palpitation [(4.43±1.80)scores vs.(11.00±1.00)scores]and chest pain [(13.25±4.00)scores vs.(20.00±3.00)scores]etc.after implantation of dual-chamber pacemaker,P<0.05 all;there were significant improvements in heart function indexes [cardiac output:(4.12±1.00)L/min vs.(6.90±3.00)L/min,left ven-tricular ejection fraction:(29.80±4.00)% vs.(38.00±3.00)%,cardiac index:(3.20±0.81)L·min-1 ·m-1 vs.(4.31±0.45)L·min-1 ·m-1 ,P<0.01 all],and significant increase in each score and total score of QOL [(12.50±1.00)scores vs.(20.50±2.20)scores]on the third month,and continued until 6 month after implanta-tion (P<0.01 all)in patients with bradyarrhythmia.Conclusion:Dual-chamber pacemaker can significantly im-prove heart function and quality of life in patients with bradyarrhythmia and should be extended in clinic.%目的：观察双腔心脏起搏器治疗缓慢性心律失常的效果、分析其对心功能的影响。方法：选择86例缓慢性心律失常且行双腔心脏起搏器植入术患者，随访6个月，以 Karolinska调查问卷评价症状积分，观察其症状积分、心功能及生活质量改善情况。结果：与植入前比较，双腔心脏起搏器植入后，患者气短乏力[（7.20±5.50）分比（15.00±4.30）分]、头晕[（3.45±2.20）分比（7.80±1.40）分]、心悸[（4.43±1.80）分比（11.00±1.00）分]和胸痛[（13.25±4.00）分比（20.00±3.00）分]等症状积分显著提高（P均＜0.05）；3个月时心功能[心输出量：（4.12±1.00）L/min比（6.90±3.00）L/min，左室射血分数：（29.80±4.00）％比（38.00±3.00）％，心脏指数（3.20±0.81）L·min-1·m-1比（4.31±0.45）L·min-1·m-1]等各项指标明显改善（P均＜0.01），生活质量各项评分及总分[（12.50±1.00）分比（20.50±2.20）分]显著提高（P 均＜0.01），并持续到术后6个月。结论：双腔心脏起搏器能明显改善缓慢性心律失常者症状、心功能、提高其生活质量，值得推广使用。
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