120例早期与非早期急性冠状动脉综合征患者临床特征分析

摘要

Objective:To compare and analyze clinical features between patients with early and non‐early acute coro‐nary syndrome (ACS) .Methods :A total of 120 ACS patients were selected ,including 71 patients with early ACS (early ACS group ,onset time≤12h) and 49 patients with non‐early ACS (non‐early ACS group ,onset time >12h) . Risk factors ,clinical features ,mortality ,incidence rates of myocardial infarction ,rehospitalization and major ad‐verse cardiovascular events (MACE) were compared and analyzed between two groups .Results:There were no sig‐nificant difference in percentage of each ACS risk factor between two groups , P>0.05. Compared with non‐early ACS group ,there was significant reduction in incidence rate of heart failure (73.5% vs .54.9% ) ,significant rise in incidence rates of obvious chest pain (32.7% vs .73.2% ) and shock (46.9% vs .62.0% ) in early ACS group (P<0.05 all) ,but there was no significant difference in incidence rate of arrhythmia between two groups (P>0.05) . After one‐year follow‐up , compared with non‐early ACS group , there were significant reduction in mortality (18.4% vs .4.2% ) ,incidence rates of myocardial infarction (18.4% vs .4.2% ) ,rehospitalization (30.6% vs . 14. 1% ) and MACE (38. 8% vs .16. 9% ) in early ACS group , P<0. 05 all .Conclusion:Initial symptom is more ob‐vious ,but related complications are fewer and the prognosis is better in patients with early acute coronary syndrome .%目的：比较分析早期与非早期急性冠状动脉综合征（ACS）患者的临床特征。方法：选择ACS患者120例，其中早期ACS患者71例（早期ACS组，发病时间≤12h），非早期ACS患者49例（非早期ACS组，发病时间＞12h）。分析比较两组患者危险因素，临床特征、死亡率、心肌梗死、再住院以及主要不良心血管事件发生率等情况。结果：两组各ACS危险因素比例无显著性差异（ P＞0.05）。与非早期ACS组比较，早期ACS组患者心力衰竭发生率（73.5％比54.9％）显著降低，明显胸痛（32.7％比73.2％）和休克发生率（46.9％比62.0％）显著升高（P均＜0.05），而心律失常发生率在两组之间无显著性差异（P＞0.05）。随访一年后，与非早期ACS组比较，早期ACS组患者的死亡率（18.4％比4.2％）、心肌梗死（18.4％比4.2％）、再住院率（30.6％比14.1％）和主要不良心血管事件发生率（38.8％比16.9％）均显著降低（P均＜0.05）。结论：早期急性冠状动脉综合征患者首发症状更为明显，相关并发症较少，预后较好。