目的 探讨身体成分各指标在甲亢患者应用抗甲状腺药物前后的变化,探讨抗甲状腺药物(ATD)对患者身体成分的影响及相关性.方法 随机抽取89名未经治疗的女性甲亢患者,对其体成分数据按照治疗前后进行分期对比测量,同时与健康对照组对比,对数据进行处理分析.结果 甲亢组与对照组相比血清FT3、FT4明显升高,TSH明显降低;经MMI治疗后甲亢组FT3、FT4水平较治疗前均明显下降,sTSH、体质量、脂肪量、肌肉量、脂肪含量百分比较治疗前均明显上升,骨量和全身水重量无明显变化.结论 本研究可以为提高病患生活质量提供理论依据,同时也可为临床医生提出可行的新的诊疗思路.%Objective To explore the changes of body composition in female hyperthyreosis patient and to explore the influence and relevance of anti-thyroid drugs (ATD) on the body composition of patients. Methods 89 women with untreated hyperthyroidism was selected and their body composition data were measured and compared before and after treatment. At the same time compared with healthy people. Results The serum FT3 and FT4 in the hyperthyroidism group were significantly higher than that in the healthy group, but TSH was significantly decreased. After treatment with MMI, the FT3, FT4 levels were significantly lower. The sTSH, body weight, body fat, muscle mass, fat percentage were significantly increased compared with before treatment. There was no obvious change in the bone mass and body water weight. Conclusion This research could provide a theoretical basis for improving the patients' quality of life and feasible new treatment ideas for clinicians.
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