中药活血化瘀法对低灌注/栓子清除能力下降型脑梗死患者脑血流灌注量的影响

摘要

目的 研究灯盏花素针对低灌注/栓子清除能力下降型脑梗死患者脑血流灌注量的影响.方法 选取本院100例低灌注/栓子清除能力减小型脑梗死病例作为研究对象,随机均分为2组,对照组使用常规西药,实验组加用灯盏花素针,比较2组血浆D二聚体(D-D)、纤维蛋白原(Fib)、收缩压、舒张压、神经功能恢复效果.结果 实验组D-D、Fib水平、NIHSS评分均明显小于对照组(P＜0.05),且收缩压明显高于对照组(P＜0.05).结论 灯盏花素针可降低低灌注/栓子清除能力减小型脑梗死患者血浆D-D与Fib浓度,增加脑血流灌注量,有效改善神经功能损伤情况.%Objective To study the effect of breviscapine injection on cerebral blood perfusion in patients with hypoperfusion/decreased embolic clearance type cerebral infarction.Methods 100 patients with hypoperfusion/decreased embolic clearance type cerebral infarction in our hospital were selected and randomly divided into two groups.Both group were treated with conventional western medicines, and the experimental group was additionally treated with breviscapine injection.The plasma D-dimer (D-D), fibrinogen (Fib), systolic and diastolic blood pressure and recovery of neurological function were compared between the two groups.Results D-D and Fib levels and NIHSS score in the experimental group were significantly lower than those in the control group (P< 0.05), while the systolic blood pressure was significantly higher than that in the control group (P< 0.05).Conclusion Breviscapine injection can reduce the plasma D-D and Fib levels, increase cerebral vascular blood flow and improve the neurological function in patients with hypoperfusion/decreased embolic clearance type cerebral infarction.