红斑性肢痛症8例临床分析

摘要

Objective To investigate the etiology, pathogenesis and treatment of erythromelalgia.MethodsRetrospective analysis of clinical features and respective treatment options of 8 cases of erythromelalgia patients in Ruijin Hospital.ResultsThe major clinical characteristics of EM cases included burning, sharp, tingling and/or stinging pain in toes, soles and/or dorsum of feet, increased temperature, erythema and swelling.One case reported burning pain in both fingers and feet.These symptoms were more severe during the night, walking, standing, exercising and when the individual was near a heater.Patients could relieve their pains by rest, using cold packs, walking on cold floors or immersing feet in cold water.Combined treatment, topical therapies and management of underlying disorders were necessary for erythromelalgia.ConclusionErythromelalgia is a rare cutaneous vascular disease with characteristics of recurrent redness, burning pain, and warmth of the extremities which could be induced by heat and exercise.Combined treatment, topical therapies and management of underlying disorders were necessary for erythromelalgia.%目的 探讨红斑性肢痛症的病因、发病机制及治疗.方法 对上海交通大学医学院附属瑞金医院皮肤科病房收治的8例红斑性肢痛症患者的临床资料进行回顾性分析,总结分析患者的临床特征及各自治疗方案.结果 病例中发病部位以足部为多,一例患者累及手指和双足,表现为胀痛、灼痛、刺痛,皮肤潮红、红斑或肿胀、发绀,皮温增高.以上症状以夜间、行走、劳累后和遇热明显,休息、遇冷及冷敷后减轻.治疗上多需联合治疗,并加强皮肤护理.结论 红斑性肢痛症是一种由微热和运动促发的阵发性肢端皮肤扩张潮红、局部温度升高、伴灼热和疼痛为特征的少见皮肤脉管性疾病.治疗上多需联合治疗,并加强皮肤护理;继发性红斑性肢痛尚需同时治疗原发病.