艾灸配合川芎嗪治疗寒湿凝滞型慢性盆腔炎疗效及对CRP、IL-6和TNF-α的影响

摘要

Objective:To observe the effect of moxibustion combined with ligustrazine in the treatment of cold-damp type pelvic inflammatory disease and its influence on serum CRP,IL-6 and TNF-a.Methods:84 cases of cold-damp type chronic pelvic inflammation patients were randomly divided into the observation group and the control group,42 cases for each,the control group was treated with ligustrazine injection for intravenous drip,the observation group were treated with moxibustion based on the control group.The clinical effects and the levels of CRP,IL-6,TNF-alpha in two groups before and after the treatment were compared.Results:The CRP,IL-6,and TNF-α levels of two groups before the intervention had no significant difference,after intervention,the total effective rate of observation group (95.24％) was higher than that of the control group (83.33％),the level of serum inflammatory factors in two groups showed significant change after treatment,but the extent of the observation group was more obvious than the control group.Conclusion:Moxibustion combined with ligustrazine therapy has a good curative effect on chronic pelvic inflammation,disease of cold-damp coagulation type,significantly reduce levels of CRP,IL-6,TNF-α and control the patient's infection status.%目的:观察艾灸配合川芎嗪治疗寒湿凝滞型慢性盆腔炎的疗效及其对血清CRP、IL-6和TNF-α水平的影响.方法:将84例寒湿凝滞型慢性盆腔炎患者随机分为观察组和对照组各42例.对照组单纯给予静脉滴注川芎嗪注射液治疗,观察组在对照组的基础上加用艾灸治疗,比较2组患者的临床疗效及治疗前后炎性因子CRP、IL-6和TNF-α水平的变化.结果:治疗前2组患者的CRP、IL-6和TNF-α水平比较差异无统计学意义;治疗后观察组总有效率95.24％高于对照组83.33％,2组的血清炎性因子水平均出现明显变化,但观察组的变化幅度较对照组更明显.结论:艾灸与川芎嗪两者配合使用治疗寒湿凝滞型慢性盆腔炎具有较好的疗效,可显著降低患者的CRP、IL-6、TNF-α水平,更加有效地控制患者的感染状况.