不同运动干预方式对糖尿病前期人群血糖相关指标影响的Meta分析

摘要

目的:系统评价有氧运动、抗阻运动、有氧联合抗阻运动三种不同干预方式对糖尿病前期人群血糖的影响.方法:制定文献检索策略,检索PubMed、EMBASE、EBSCO外文数据库以及CNKI、Wanfang中文数据库,以手工查阅检出文献和相关参考文献作为补充,查找符合纳入标准的随机对照试验进行质量评价,运用RevMan5.2统计软件对纳入的数据进行Meta分析,运动干预组和对照组间指标采用均数差(MD)评价.结果:共纳入原始文献8篇,与对照组相比,不同运动干预方式的综合效应对空腹血糖指标无显著性影响,与按不同干预方式进行亚组分析结果一致;有氧运动及有氧联合抗阻运动对餐后2h血糖指标有显著性降低的作用(P＜0.05);有氧运动对胰岛素抵抗指数有显著降低作用.结论:对糖尿病前期人群,运动干预对餐后2h血糖、胰岛素抵抗指数的影响与运动方式有关,但对空腹血糖的作用尚不能确定.%Objective:To assess the influence of the different exercise intervention mode,aerobic exemise training(AET),resistance training(RT) and AET RT,on blood glucose of pre-diabetes.Methods:Literatures were identified from the PubMed,EMBASE,EBSCO,CNKI and Wanfang databases.Relevant journals or conference proceedings were also searched manually.The qualities of randomized controlled trials that conformed to inclusion criteria were evaluated.Meta-analysis of the obtained related data was completed utilizing RevMan 5.2 statistical software.Mean difference of index related in exercise intervention groups and control group were calculated across the studies.Results:Eight original literatures enrolled in this study.Compared with control group,combined effect of different exercise interventions on fasting blood glucose showed no significant,consistent with different intervention subgroups analysis.RT group and AET + RT group showed a significantly reduced role on 2 h postprandial blood index (P ＜ 0.05).AET group showed a significantly reduced role on insulin resistance index.Conclusion:To pre-diabetic,effects of exercise on postprandial 2 h blood glucose and insulin resistance index are related to modes of exercise.Effects of exercise on fasting blood glucose,but still could not be determined.