Forty-eight healthy yellow cattle，on whi ch catheterizations of the gallbladder a nd duodenum were performed after choledo ch being cut off，were used to cultivate calculus bovis simultaneously in the ext ernal calculus bovis generators (CBG) an d internal gallbladders．After operations the normal passage of bile excretion wa s changed from the liver，biliary duct，ga llbladder，via the gallbladder catheter a nd generator to the duodenum．The results indicated that both biliary pH value an d viscosity of the experimental cattle d ecreased，the biliary viscosity in the CB G decreased more than that in the gallbl adder．The E．coli content was decreased and the inflammation of the g allbladder was lessened after injecting benzalkoni bromidum into it．As far as th e material of calculus bovis carrier was concerned，cotton excelled both polyamid e 66 and polyester in both output and qu ality of calculus bovis．The netting-shap ed carrier filled with material could in crease the yield and improve the quality of calculus bovis．Over a period of five to seven months，the output of calculus bovis was 14．1～19．6 g per cattle and the bilirubin content in cultivated calculu s bovis was 29．05％±7．51％．%利用48头健康黄牛同时施行胆总管结扎术、胆囊插管术、十二指肠插管术和体外安装牛黄发生器，将原胆汁流通径路改建为肝脏→胆管→胆囊→引胆汁管→牛黄发生器→十二指肠，在体外牛黄发生器内和胆囊内同时培植牛黄。结果表明，植黄牛胆汁pH值降低，胆酸含量下降，牛黄发生器内胆汁粘度低于胆囊内胆汁粘度。胆囊内注入新洁尔灭，可减少胆汁中细菌数量，减轻胆囊炎症反应。全棉材料牛黄床的牛黄产量高于锦纶66和涤纶材料牛黄床，以网眼状全腔充盈型牛黄床的牛黄产量高、质量好。在5～7个月的培植期内，每头牛能生产牛黄14.1～19．6 g，牛黄胆红素含量为29.05％±7．51％。
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