This study was conducted to investigate the effects of oral N-carbamylglutamate (NCG) supplementation on growth performance,blood parameters and organ weight of suckling kidlets from 1 to 41 days of age.Thirty two suckling kidlets with similar body weight [(3.1±0.3) kg] were randomly assigned to 2 groups (16 kidlets per group) at 1 day of age.Two groups of kidlets were orally administrated NCG at the dose of 0 (control) and 100 mg/kg BW per day,respectively.All kidlets were sacrificed at 41 days of age.The results showed that compared with control group:1) oral administration of NCG significantly increased average daily gain and reduced diarrhea rate of sucking kidlets at 1 to 41 days of age (P<0.05);2) oral administration of NCG significantly increased plasma total protein and albumin contents of 41-day-old suckling kidlets (P <0.05),meanwhile,significantly decreased plasma ammonia and urea nitrogen contents of 21-and 41-day-old suckling kidlets (P<0.05);3) oral administration of NCG significantly increased plasma growth hormone,insulin and nitric oxide contents of 21-and 41-day-old suckling kidlets (P<0.05);4) oral administration of NCG significantly increased plasma arginine,citrulline and ornithine contents of 41-day-old suckling kidlets (P<0.05);5) oral administration of NCG significantly increased the relative weight of spleen,large intestine and small intestine of suckling kidlets (P<0.05).In conclusion,oral administration of NCG increases synthesis of arginine and improve growth performance of suckling kidlets.%本试验旨在研究1~41日龄哺乳山羊羔羊灌服N-氨甲酰谷氨酸(NCG)对其生长性能、血液参数及器官重的影响.选取1日龄体重[(3.1±0.3)kg]相近的哺乳山羊羔羊32只,随机分在2个组中(每组16只),按每天分别灌服0(对照)、100 mg/kg BW的NCG.于羔羊41日龄时进行屠宰.结果表明,与对照组相比:1)灌服NCG显著提高了1~41日龄羔羊平均日增重,显著降低了腹泻率(P<0.05);2)灌服NCG显著提高了41日龄羔羊血浆中总蛋白和白蛋白含量(P<0.05),而显著降低了21和41日龄羔羊血浆氨和尿素氮含量(P<0.05);3)灌服NCG显著提高了21和41日龄羔羊血浆胰岛素、生长激素及一氧化氮含量(P<0.05);4)灌服NCG显著提高了41日龄羔羊血浆精氨酸、鸟氨酸和瓜氨酸含量(P<0.05).5)灌服NCG显著提高了羔羊脾脏、小肠及大肠相对重量(P<0.05).结果提示,灌服NCG促进哺乳山羊羔羊的生长发育及内源精氨酸合成.
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机译:N-[n-(3,3-dimetilbutil)-L-α-天冬氨酰]-L-苯丙氨酸甲酯的分离和纯化方法,生产N-[n-(3),3-dimetilbutil的方法)-L-α-天冬氨酰]-L-苯丙氨酸甲酯或N-[n-(3,3--dimetilbutil)-L-α-天冬氨酰]-L-苯丙氨酸甲酯和N,n'- di (3,3-dimetilbutil)-APM.APM衍生物和甜味剂