3种药物对绵羊自然感染球虫的治疗效果

摘要

In order to determine whether or not coccidiostats currently available in poultry industry could be used in sheep, 3 chemotherapeutic compounds including diclazuril, sulfadimidine and clopidol were selected to test their efifcacy in treating naturally infected animals. The parameters, such as oocysts per gramme (OPG), animal cured rate, weight gain rate and added value of gain weight were measured to evaluate the efifcacy of coccidiostats. The results showed that all of these three drugs showed excellent treatment for coccida infection in adult sheep, in which of diclazuril was the best. In lamb, diclazuril and clopidol had excellent therapeutic efifcacy but sulfadimidine had little. These three drugs all had excellent therapeutic efifcacy against pathogenic Eimeria species, including Eimeria ahsata, E.bakuensis and E.ovinoidalis. During the experiment period, all treated groups of animals gained more weights and proifts than the untreated group.%为了筛选有效的抗绵羊球虫药物，选择地克珠利（diclazuril）、磺胺二甲嘧啶（sulfadimidine）、克球粉（clopidol）3种常用的抗鸡球虫药物，进行绵羊自然感染球虫的治疗试验，以每克粪便球虫卵囊数（oocysts per gramme，OPG）、动物转阴率、增重率、增重新增产值作为评判指标，评价其抗绵羊球虫的驱虫效果。结果表明，3种药物对成年绵羊球虫感染均具有较好的治疗效果，其中地克珠利效果最好，克球粉次之，磺胺二甲嘧啶稍差。磺胺二甲嘧啶对羔羊球虫感染的治疗效果较差，而地克珠利和克球粉均具有良好的治疗效果，且二者的效果相当。3种药物对阿撒他艾美耳球虫（Eimeriaahsata）、巴库艾美耳球虫（Eimeriabakuensis）、类绵羊艾美耳球虫（Eimeriaovinoidalis）等3种致病性羊球虫感染均具有较好的治疗效果，其中地克珠利和克球粉效果最好，而磺胺二甲嘧啶稍差。在整个试验期间，不给药组成年羊和羔羊的增重和新增产值均为负值，而三个用药组的体重和产值均增加，其中地克珠利组稍好于克球粉组和磺胺二甲嘧啶组。