CP/CPPS患者中UPOINT因子与早泄的相关性分析

摘要

Objective To investigate the correlation between chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) patients' UPOINT domains and premature ejaculation(PE).Methods Total of 186 CP/CPPS patients were enrolled and evaluated by UPOINT system. The intravaginal ejaculatory latency time and PEDT were recorded. Results Among 186 CP/CPPS patients, 42.4%were diagnosed as PE. Multivariate logistic regression showed urinary (U) domain(OR=2.890, 95%CI 1.348-4.083, P<0.05) and psychological (P) domain(OR=4.432, 95%CI 2.857-7.691, P<0.05) were independent risk factor for PE in CP/CPPS, the number of positive domains was closely correlated with PEDT. Conclusion CP/CPPS patients had a higher rate of PE occurrence.Urinary domain and psychological domain was independent risk factors of PE in CP/CPPS.%目的：探讨慢性前列腺炎/慢性盆底疼痛综合征（CP/CPPS）患者的临床表型分类系统（UPOINT）因子与早泄（PE）病情的相关性。方法对186名CP/CPPS患者进行UPOINT分类，记录其中确诊为PE患者的阴道内射精潜伏时间（IELT）并使用早泄诊断量表（PEDT）评估症状严重程度。结果186名CP/CPPS患者中，79名确诊为PE（42.4%），多元Logistic回归分析显示，排尿症状（U因子，OR＝2.890，95%CI 1.348-4.083，P＜0.05）、精神心理障碍（P因子，OR＝4.432，95%CI 2.857-7.691，P＜0.05）是CP/CPPS患者发生PE的独立危险因素，PEDT评分与患者UPOINT因子数呈正相关。结论 PE在CP/CPPS患者中发生率较高。UPOINT中的泌尿系统症状（U）和社会心理症状（P）因子是CP/CPPS患者出现PE的独立危险因素。