目的:探讨分析枕骨大孔减压联合枕颈融合术治疗寰枕畸形的临床疗效.方法:选取我院于2006年4月～ 2011年2月收治的60例寰枕畸形的患者,随机分成实验组与对照组,两组人数均为30例.对照组患者接受单纯的枕骨大孔减压术,实验组患者接受枕骨大孔减压联合枕颈融合术,观察其临床疗效.结果:对照组患者总有效率40.0％,平均住院时间(15.3±3.4)天,平均携带颈托时间(97.4±12.9)天,术后半年有7例患者神经症状复发或加重；实验组患者总有效率86.7％,平均住院时间(9.6±2.1)天,平均携带颈托时间(68.5±14.7)天,术后半年1例患者神经症状复发或加重,两组患者在手术疗效、平均住院时间,平均携带颈托时间,复发情况的差异比较均有显著性差异(P＜0.05),实验组明显优于对照组.结论:枕骨大孔减压联合枕颈融合术治疗寰枕畸形,疗效显著,对患者的预后较好,且能提高患者的生活质量,值得推广.%Objective To study the clinical curative effect of foramen magnum decrompression combined with occipitocervical fusion in the treatment of occipitocervical malformation. Methods From April, 2006- February, 2011, 60 patients with occipitocervical malformation were randomly divided into the control group and the experimental group. There were 30 cases in each group. The control group was treated with foramen magnum decrompression while the experimental group was treated with foramen magnum decrompression combined with occipitocervical fusion. Observe the clinical curative effect of the two groups. Results The total effective rate of the control group was 40.0%, the average hospital time was (68.5±14.7) days, the average time of wearing the cervical collar was (97.4± 12.9) days , and 6 months after the surgery, 7 patients relapsed; the total effective rate of the experimental group was 86.7%, the average hospital time was (9.6±2.1) days, the average time of wearing the cervical collar was (68.5±14.7) days, and 6 months after the surgery, 1 patients relapsed. The difference of total effective rate, average hospital time, average time of wearing the cervical collar and recurrence between the control group and the experimental group was statistically significant (P<0.05) and the experimental group was obviously better than the control group. Conclusion Foramen magnum decrompression combined with occipitocervical fusion has a significant effect in the treatment of occipitocervical malformation, which can improve the quality of life and do good to the prognosis of the patients.
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