目的：探讨平阳霉素联合肾上腺素注射液治疗瘢痕疙瘩的临床疗效，为瘢痕疙瘩的临床治疗提供依据。方法：选取笔者科室2014年5月-2015年1月收治的62例瘢痕疙瘩患者，将患者随机分为两组，对照组：31例，采用平阳霉素进行治疗；观察组：31例，采取平阳霉素联合肾上腺素注射液治疗，比较两组患者的临床疗效。结果：观察组治疗总有效率87.10%，显著高于对照组的74.19%，两组患者治疗总有效率比较，差异有统计学意义（P＜0.05）；所有患者均获得为期12个月的随访，观察组复发率6.45%，对照组复发率16.13%，两组患者复发率比较，差异有统计学意义（P＜0.05）；观察组在面颈部、臀部治疗上疗效与对照组相似（P＞0.05），但在背部、胸口、腹部和四肢的疗效上比较显著优于对照组，差异有统计学意义（P＜0.05）。结论：平阳霉素联合肾上腺素注射液治疗瘢痕疙瘩疗效显著且复发率低，值得临床推广使用。%Objective To study the joint adrenaline pingyangmycin injection in the treatment of keloid effect, provide the basis for clinical treatment of keloid. Methods Selection our hospital from May 2014 to January 2015, 62 cases of keloid patients as the research object, according to the number of random methods patients were randomly divided into two groups, 31 cases were treated by pingyangmycin and observation group, 31 cases treated with pingyangmycin joint epinephrine injection, compared two groups of patients with clinical efifcacy. Results The observation of treatment group total effectiveness 87.10%, signiifcantly higher than that of control group 74.19%, total effective rate of two groups of patients, compared the difference was statistically signiifcant (P<0.05). All patients get the 12-month follow-up, observation group recurrence rate was 6.45%, control group recurrence rate was 16.13%, compared two groups of patients with recurrence, the difference was statistically signiifcant (P<0.05). In observation group in the face and neck and hip treatment curative effect is similar to the control group (P>0.05);But in the back, chest, abdomen, and extremities on the curative effect of signiifcantly better than control group, the difference was statistically signiifcant (P<0.05). Conclusion Pingyangmycin joint epinephrine injection keloid with obvious therapeutic effect and low recurrence rate, worthy of clinical promotion use.
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