目的:探讨富血小板血浆(Platelet rich plasma,PRP)结合自体脂肪移植在面部凹陷填充中的应用及其并发症情况.方法:本组共65例就医者,于大腿根部内侧获取自体脂肪并纯化,静脉采血经处理获得PRP,PRP与自体脂肪按1:3比例混合后注射于面部凹陷处.结果:术后随访6～12个月,其中64例对术后效果满意,1例自觉改善不明显术后半年行二次填充,所有就医者均未出现脂肪液化、感染、坏死、血肿、结节等并发症.结论:PRP结合自体脂肪移植应用于面部凹陷填充疗效确切,并发症可控,脂肪存活率较高,值得临床应用.%Objective To investigate the application of platelet rich plasma(PRP) combined with autologous fat-free transplantation in the filling of facial depression, and analysis of its complications. Methods In 65 patients, the autologous fat was obtained from the inside of thigh root and purified. Venous blood was collected and processed to obtain PRP, PRP was mixed with autologous fat in proportion 1:3 and then injected into facial depression. Results All patients were followed up for 6-12 months. 64 cases were satisfied with the postoperative effect, one case was no significant improvement and second operations were filled six months after the operation. All patients did not appeared fat liquefaction, infection, necrosis, hematoma, nodules and other complications. Conclusion The application of PRP combined with autologous fat free transplantation in facial filling is effective, with controllable complications, and increased fat survival rate, which is worthy of clinical application.
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