妊娠期高血压疾病与胎儿血流动力学的关系

摘要

目的：探讨孕晚期胎儿大脑中动脉和脐动脉阻力指标及比值与妊娠期高血压疾病的关系。方法：运用彩色多普勒超声检测80例胎龄34～40周的正常胎儿和88例母体患妊娠期高血压疾病胎儿的大脑中动脉和脐动脉的搏动指数（PI）、RI、收缩期峰值流速与舒张末期流速比值（S/D）。88例妊娠期高血压组又分为轻度组与重度组。对正常组、轻度组、重度组的阻力指标与比值结果行统计学分析。结果：正常组与妊娠期高血压疾病轻度组阻力指标及比值比较，差异均无统计学意义（均P>0.05）；正常组与妊娠期高血压疾病重度组比较，差异均有统计学意义（均P<0.01）；妊娠期高血压疾病轻度组与重度组比较，差异均有统计学意义（均P<0.05）。结论：晚期妊娠胎儿大脑中动脉和脐动脉各项阻力指标比值与妊娠期高血压疾病严重程度有一定的相关性。随着妊娠期高血压疾病的加重，胎儿脐动脉3个阻力指标升高，胎儿大脑中动脉3个阻力指标及与脐动脉阻力指标比值降低。%Objective:To study the relationship between uterine artery score and infant middle cerebral artery blood floor waveforms in women with pregnancy-induced hypertension. Methods:Eighty normal fetuses between 34 and 40 weeks of gesta-tion and 88 fetuses with maternal hypertension were measured for MCA and UA pulsatility index (PI),resistance index (RI) and the peak-systolic/diastolic ratio (S/D) by means of color Doppler ultrasonography,and the resistance index ratio was calculated. Results:There was no statistical significance of resistance index and ratio between normal group and mild gestational hyperten-sion group (P>0.05),while significant difference existed between normal group and severe gestational hypertension group (P<0.01). Significant difference also existed between mild gestational hypertension group and severe group (P<0.05). Conclusions:The resistance index ratio of fetal MCA and UA has certain correlation with the severity of hypertensive disorders in late preg-nancy. With gestational hypertension disease is aggravating,three fetal umbilical artery resistance index increase,3 fetal umbilical artery resistance index increase,and the 3 ratio of middle cerebral artery resistance index and umbilical artery resistance index decrease.