Synthesis and Application of Novel Chiral Noncyclic Crown Ether Bisoxazoline and Bisthiazoline ligands

摘要

A series of novel C2-symmetrical chiral bis (oxazoline)and bis(thiazoline)ligands containing noncyclic crown ether type was synthesized.Their structures were determined by IR spectra,1H nuclear magnetic resonance(NMR),13C NMR,and elemental analysis.The copper complexes of the above ligands were used in catalytic asymmetrical Henry reactions.Enantioselectivities up to 33% were observed.