虎力散胶囊应用于骨关节术后的临床疗效研究

摘要

Objective To explore the clinical value of Huli San Capsules in repairing trauma and preventing complications after orthopaedic surgery. Methods Totally 120 patients who had undergone same orthopaedic surgery were equally and randomly divided into Huli San Capsules ( 0. 3 g per capsule , twice a day ) ( HLS ) group and control group ( diclofenace acetate tablet, 50 mg per tablet ) . The response criteria were evaluated using Modified Lysholm Score. while the functional evaluation was performed using Visual Analogue Scale and Kujala Score. Results All patients after treatment were followed up for 12 ～ 19 months ( mean : 16. 5 months ) . The effectiveness. VAS score , and Kujala score between the two groups were significantly different between two groups ( P ＜0. 01 ) . Conclusion Huli San Capsules can promote the recovery of the soft tissue and reduce the scar adhesion of joints after orthopedic surgery with low incidences of adverse events.%目的 探讨虎力散胶囊(Huli San Capsules)对骨关节术后创伤俢复及并发症预防的疗效及临床意义.方法 将120例骨关节手术方式相同的患者,随机分为治疗组(60例)和对照组(60例),在同等住院条件下治疗2周,治疗组采用口服虎力散胶囊(云南云河药业有限公司,0.3 g/粒),1粒/次,2次/d,2周为1个疗程.对照组采用口服双氯芬酸钠肠溶片(Diclofenace Acetate Tablets,50 mg/粒),1粒/次,2次/d,2周为1个疗程.疗效评价标准参照改良利斯霍姆评分标准,功能评定应用视觉模拟(VAS)评分法及关节库亚拉(Kujala)评分标准.结果 治疗后患者均得到随访,平均随访16.5个月(12～19个月).两组患者治疗后疗效比较,差异有统计学意义(P＜0.01);治疗后关节VAS评分、Kujala评分比较,差异均有统计学意义(P＜0.01);两组不良反应发生率比较,差异有统计学意义(P＜0.01).结论 虎力散胶囊可以有效促进骨科无菌术后软组织康复,减少关节瘢痕粘连等功能障碍,而且不良反应发生率较低.