系统性红斑狼疮患者动脉粥样硬化发病机制的研究进展

摘要

Systemic lupus erythematosus (SLE) is a kind of autoimmune diseases mainly occurring in young females. In recently years, with the progress of clinical treatment, SLE prognosis has been greatly enhanced, and the causes of late death (5 years after diagnosis) are drawing increasing attention. As a major complication, atherosclerosis has become a hotspot in recent academic community. This paper reviews studies on the pathogenesy of atherosclerosis in SLE patients.%系统性红斑狼疮(SLE)是一种主要发生于年轻女性的自身免疫性疾病.近年来,随着临床治疗水平的提高,患者预后明显改善,远期死亡(诊断5年后)原因越发得到关注.作为SLE远期主要并发症的动脉粥样硬化,近年来成为研究热点.本文对SLE中动脉粥样硬化发病机制的研究进展进行综述.