代餐饮食在糖尿病中的应用研究进展

摘要

Diabetes mellitus (DM) is a public health problem that threatens the health of all mankind.It not only affects the health of patients with a shortened life,but also increases the economic burden on individuals and countries.Over the past 30 years,the prevalence of diabetes in China has increased rapidly while patients tend to be younger.At present, more than 90% of diabetic patients suffered from type 2 diabetes.Relevant studies have shown that meal replacement diet can effectively improve the blood glucose and blood lipid level of overweight or obese patients with type 2 diabetes,and reduce patients' body mass and waistline.Meanwhile,meal replacement diet is conducive to the HbA1cand improves patient compliance and satisfaction,which achieves the intervention and treatment of DM in many ways.But the mechanism of meal replacement diet in treatment of type 2 diabetes is not yet entirely clear,and there are relatively few studies at home and abroad on this aspect. Therefore this paper summarizes the current studies to review the progress of this kind of study.%糖尿病是目前威胁全人类健康的公共卫生问题,不但影响患者的健康、缩短患者的寿命,而且增加了个人和国家的经济负担.近30年来,我国糖尿病患病率快速增长,且趋于年轻化.目前糖尿病患者中90%以上为2型糖尿病.研究表明,代餐饮食能有效改善超重或肥胖2型糖尿病患者的血糖、血脂水平,减轻体质量,缩小腰围,利于糖化血红蛋白达标和提高患者的依从性和满意率,在多方面达到干预及治疗的效果.但代餐饮食治疗超重或肥胖2型糖尿病及糖尿病前期患者的机制尚未完全明确,国内外研究相对较少,本文现对目前的研究进展作一综述.