老年高血压患者发生颈动脉粥样硬化的相关性分析

摘要

Objective:To explore the association between blood pressure and carotid atherosclerosis in elderly patients with essential hypertension. Methods:A total of 120 patients aged 60 years or over with hypertension,detection with carotid atherosclerosis-related factors,such as the level of blood pressure,blood sugar,cholesterol,body mass index;Carotid ultrasonography was performed in all subjects for the evaluations of intima-media thickness(IMT) and plaque.Results:Multiple linear regression analyses revealed that Systolic blood pressure,total cholesterol,fasting blood glucose and carotid carotid intima thickness was positively correlated,and high-density lipoprotein cholesterol with carotid carotid intima thickness was negatively correlated.The analysis showed that the systolic blood pressure≥140 mm Hg,total cholesterol as a risk factor for carotid plaque formation,and high-density lipoprotein cholesterol for its protective factors.Conclusion:High blood pressure and high cholesterol is the risk factor for carotid atherosclerosis in elderly patients.%　　目的：探讨血压水平与原发性高血压患者颈动脉粥样硬化的关系。方法：120例患有原发性高血压年龄>60岁的患者，检测与颈动脉粥样硬化形成的相关因素，如血压水平、血糖、胆固醇、体重指数等。对每位患者进行颈动脉超声检查，记录颈动脉内中膜层的厚度。结果：多因素线性回归分析显示，收缩压、总胆固醇与颈动脉内中膜厚度呈正相关，而高密度脂蛋白胆固醇与颈动脉内中膜厚度呈负相关。分析显示，收缩压≥140 mm Hg 和总胆固醇升高为颈动脉粥样斑块形成的危险因素，而高密度脂蛋白胆固醇为其保护性因素。结论：高血压和胆固醇升高是颈动脉粥样硬化及斑块形成的危险因素。