血清C反应蛋白对于慢性肝病诊断的临床意义

摘要

Objective:To study the clinical significance of serum C reactive protein(CRP) for the diagnosis of chronic hepatic disease.Method:The serum CRP levels and the positive rate were detected by the rate nephelometry and compared for the 98 cases of chronic hepatic patients including the 22 cases of chronic hepatitis,41 cases of liver cirrhosis,35 cases of liver cancer and 98 cases of health persons in our hospital during the period from Feb 2012 to Feb 2014. Result:Compared with the health persons,the serum CRP levels and the positive rates were significantly increased in chronic hepatic patients(P<0.05);the comparisons of serum CRP levels in the chronic hepatitis,liver cirrhosis,liver cancer were statistical significance(P<0.05),liver cancer>liver cirrhosis>chronic hepatitis.Conclusion:The serum CRP detection can provide the reference basis for the clinical diagnosis of chronic hepatic disease.%目的：探讨血清C反应蛋白检测在慢性肝病诊断中的临床意义。方法：2012年2月-2014年2月，社区卫服中心诊治的98例慢性肝病患者，包括22例慢性肝炎、41例肝硬化及35例肝癌患者，以及98例健康体检者，通过速率散射比浊法，检测和比较各组血清C反应蛋白水平及阳性率。结果：与健康者相比，慢性肝病患者血清C反应蛋白水平及阳性率均明显高(P<0.05)；慢性肝炎、肝硬化、肝癌患者之间的血清C反应蛋白水平比较，差异有统计学意义(P<0.05)，依次为肝癌>肝硬化>慢性肝炎。结论：血清C反应蛋白检测，能够为慢性肝病的临床诊断提供参考依据。