睾丸畸胎瘤57例临床病理分析

摘要

Objective:To study the clinicopathological features of testicular teratoma.Method:The clinical pathological data of 57 cases with testicular teratoma were retrospectively analyzed.Result:The age of patients were 1.5 months to 43 years old,average 12.8 years,9.5-14 years old(82.5%).Clinically,thepatients were mainly present painless mass in the scrotum,accounting for 89.5%.Mature teratoma was 6 cases(10.5%),unmature teratoma was 51 cases(89.5%) patients,including simple immature teratoma of 24 cases(42.1%),merging other germ cell tumors of 27 cases(47.4%),including 14 cases of yolk sac tumor with seminoma,accounting for 24.6%,and merger of yolk sac tumor in 5 cases,accounting for 8.8%,the rest was embryonal carcinoma 2 cases,and containing at the same time the seminoma,yolk sac tumor and embryonal carcinoma was 2 cases,accounting for 3.5%.The most common clinical stage Ⅰ,accounting for 66.7%.Conclusion:Testicular teratoma are relatively rare,in the majority with before puberty,more performance for testicular painless swelling,pathological classification is immature teratoma,the most common type of cancer merger other germ cell tumor.Pathological classification and clinical stage are particularly important for the treatment and prognosis of patients.%目的：探讨睾丸畸胎瘤的临床病理特征。方法：回顾性分析57例睾丸畸胎瘤的临床病理资料。结果：57例患者，年龄1.5个月~43岁，平均12.8岁，其中9.5~14岁47例，占82.5%，单侧最多见55例，占96.5%。临床主要表现为阴囊内无痛性肿物51例，占89.5%，也可无明显症状。57例患者中，成熟性畸胎瘤6例，占10.5%，未成熟性畸胎瘤51例，占89.5%，其中单纯性未成熟畸胎瘤24例，占42.1%，合并其他生殖细胞肿瘤27例，占47.4%，其中合并精原细胞瘤和卵黄囊瘤14例，占24.6%，合并卵黄囊瘤5例，占8.8%，合并精原细胞瘤4例，占7.0%，其余为混合胚胎性癌2例和同时混合精原细胞瘤、卵黄囊瘤、胚胎性癌2例，分别占3.5%；临床分期Ⅰ期最多见38例，占66.7%。结论：睾丸畸胎瘤相对少见，患者以青春期前居多，多表现为睾丸无痛性肿大，病理分型以未成熟型畸胎瘤最常见，部分肿瘤合并其他生殖细胞肿瘤，病理分级及临床分期对患者治疗和预后尤为重要。