复方枣仁胶囊联合阿普唑仑治疗原发性失眠症临床疗效分析

摘要

Objective:To investigate the clinical curative effect of Compound Spine Date Seed Capsule on adjunctive therapy of primary insomnia. Method:82 cases of patients with primary insomnia were selected and randomized into the control groups and the treatment groups,41 cases in each group. Patients in the control group were given Alprazolam and Patients in the treatment group were given Compound Spine Date Seed Capsule combined Alprazolam,and clinical effective rate were contrasted after 3 weeks,sleeping quality were evaluated with Pittsburgh sleep quality index(PSQI) before and after treatment of two groups.Result:After 3 weeks,clinical effective rate was 95.1% in the treatment group and was 82.5% in the control group,and clinical effective rate was higher in the control group than in the treatment group(P<0.05),all index of PSQI were identical between two groups before treatment(P>0.05),after 3 weeks,score of sleeping quality,fall-sleep time,sleeping time,sleep efficiency,sleep disorder,sleep medicine and daytime function were higher of the treatment group than those of the control group(P<0.05).Conclusion:Compound Spine Date Seed Capsule could improve the clinical curative effect on patients with primary insomnia, and improve sleeping quality,and has a well clinical curative effect.%目的：探讨复方枣仁胶囊辅助治疗原发性失眠症的临床疗效。方法：选择82例原发性失眠症患者，按照随机数字表法分为对照组与治疗组，每组患者41例，对照组给予阿普唑仑治疗，治疗组给予复方枣仁胶囊联合阿普唑仑治疗，3周后比较两组患者临床有效率，采用匹兹堡睡眠质量指数(pittsburghsleep qualityindex，PSQI)评价两组患者治疗前后睡眠质量。结果：治疗3周后，治疗组临床有效率为95.1%，对照组临床有效率为82.5%，治疗组临床有效率高于对照组(P<0.05)。两组患者治疗前PSOI各指数评分比较，差异均无统计学意义(P>0.05)，治疗3周后，治疗组患者睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍、催眠药物及日间功能各因子评分高于对照组(P<0.05)。结论：复方枣仁胶囊能够改善原发性失眠症患者睡眠临床治疗效果，提高睡眠质量，具有较好的临床疗效。