新型胰岛素增敏剂对急性心肌梗死炎症因子的抑制作用探析

摘要

目的：分析和研究新型胰岛素增敏剂对急性心肌梗死炎症因子的抑制效果。方法：选取2012年8月-2014年4月笔者所在医院收治的急性心肌梗死患者82例，将其按照随机数字表法分为对照组与观察组，每组41例。对照组患者给予常规对症治疗，观察组患者在对照组治疗基础上加用吡格列酮进行治疗，将两组患者治疗后炎症因子及心功能变化情况进行对比。结果：治疗4周后，观察组患者炎症因子和心功能指标均明显优于对照组(P<0.05)。结论：将新型胰岛素增敏剂应用于急性心肌梗患者治疗中，其能够有效抑制患者炎症反应，改善患者心功能，降低心肌损害程度，对提高治疗效果具有重要作用。%Objective:To analyze and study the inhibitory effect of New Insulin Sensitizers for inflammatory cytokines of acute myocardial infarction.Method:We selected 82 cases of acute myocardial infarction from August 2012 to April 2014 in our hospital,they were randomly divided into the control group and the observation group,41 patients in each group.The control group was treated with conventional symptomatic treatment,on the base of the control group,the observation group was given Pioglitazone.The inflammatory factors and cardiac function of two groups were compared after treatment.Result:After 4 weeks,the inflammatory cytokines and cardiac function of the observation group were significantly better than those of the control group(P<0.05).Conclusion:New Insulin Sensitizers in the treatment of acute myocardial infarction can effectively inhibit the inflammatory response of patients,improve cardiac function and reduce myocardial damage,for improving the treatment effect has an important role.