上消化道疾病患者幽门螺杆菌感染现状分析

摘要

目的：了解上消化道疾病患者幽门螺杆菌的感染现状，为临床预防和诊治提供依据。方法：选取笔者所在医院2010年1月-2014年12月诊治的890例上消化道疾病患者为研究对象，分析患者幽门螺杆菌总体感染情况，比较幽门螺杆菌感染与性别、年龄的关系。结果：上消化道疾病患者幽门螺杆菌总体感染率为72.2%，男性幽门螺杆菌感染率为79.6%，显著高于女性的65.0%，差异有统计学意义(P<0.05)。老年组幽门螺杆菌感染率为75.6%，略高于中青年组的71.0%，但差异无统计学意义(P>0.05)。反流性食管炎患者幽门螺杆菌感染率最低，为60.0%，与浅表性胃炎患者的65.9%相比差异无统计学意义(P>0.05)。糜烂出血性胃炎、慢性萎缩性胃炎、消化性溃疡、胃癌患者幽门螺杆菌感染率分别为79.5%、81.6%、94.3%、84.6%，均显著高于反流性食管炎患者，差异均有统计学意义(P<0.05)。结论：上消化道疾病患者幽门螺杆菌感染率高，男性易感，应加强幽门螺杆菌知识宣传，同时根据患者病情和幽门螺杆菌检测结果采取相应的治疗方案。%Objective:To understand current status of helicobacter pylori infection in patients with upper gastrointestinal disease,and to provide the basis for clinical prevention and treatment.Method:From January 2010 to December 2014,890 patients with upper gastrointestinal disease treated in our hospital were selected.The overall infection status and each infection status were analyzed.The relationship between helicobacter pylori infection and genders,ages was compared. Result:The overall helicobacter pylori infection rate of patients with upper gastrointestinal disease was 72.2%.The helicobacter pylori infection rate of men was 79.6%,which was significantly higher than 65.0%of women,and the difference was statistically significant(P<0.05).The helicobacter pylori infection rate in elderly patients was 75.6%,which was slightly higher than 71.0%of the young group,but there wasn’t statistical significance(P>0.05).The rate of helicobacter pylori infection was lowest in patients with reflux esophagitis,about 60.0%with no significant difference compared with 65.9%of patients with superficial gastritis. The rates of helicobacter pylori infection in patients with erosive hemorrhagic gastritis,chronic atrophic gastritis,peptic ulcer and gastric cancer were respectively 79.5%,81.6%,94.3%and 84.6%,which were all significantly higher than that of reflux esophagitis patients(P<0.05).Conclusion:The helicobacter pylori infection in patients with upper gastrointestinal disease is high and males are susceptible.Helicobacter pylori knowledge propaganda shall be strengthened.At the same time,the corresponding treatment should be applied according to patients’ condition and helicobacter pylori inspection result.