大剂量氯吡格雷对急性前壁心肌梗死行急诊经皮冠脉介入治疗术后疗效

摘要

Objective:To explore the clinical curative effect of large dose clopidogrel on acute anterior myocardial infarction after emergency percutaneous coronary intervention(PCI) treatment.Methods:82 patients with acute anterior myocardial infarction were selected.They were treated with emergency PCI.They were divided into the observation group and the control group with 41 cases in each.The observation group was given large dose clopidogrel.The control group was given conventional dose clopidogrel.The disease influence and the medication safety of two groups were observed.Results:After 3 months of treatment,the left ventricular function improvement degree of the observation group was better than that of the control group,and the adverse cardiovascular event during follow-up in the observation group was significantly lower than that of the control group(P<0.05).Conclusion:Large dose clopidogrel on acute anterior myocardial infarction after PCI treatment can effectively reduce the incidence of postoperative various adverse events,and promote the recovery of cardiac function.%目的：探讨大剂量氯吡格雷对急性前壁心肌梗死行经皮冠脉介入术(PCI)治疗的临床疗效。方法：收治急性前壁心肌梗死患者82例，均行急诊PCI治疗，分为观察组与对照组各41例，观察组给予大剂量氯吡格雷，对照组给予常规剂量氯吡格雷。观察两组患者的病情影响以及用药安全性。结果：治疗3个月后，观察组左心室功能好转程度较优于对照组，且观察组在随访期间心血管不良事件明显少于对照组(P＜0.05)。结论：大剂量氯吡格雷对急性前壁心肌梗死行PCI术治疗可有效降低术后各种不良事件的发生率，促进心功能恢复。