Sonic hedgehog通路与肝细胞癌的研究进展

摘要

SHH通路与肿瘤的发生具有密切的关系,在由内胚层形成的组织器官肿瘤中常过度表达.最新研究表明,SHH通路与肝细胞癌(HCC)也存在密切联系,本文就SHH通路与HCC的研究进展作一综述.%Sonic hedgehog(SHH) pathway relates to the occurrence of cancer closely, which is overexpressed in endodermal organ of tumor. Recent research shows that SHH pathway is also closed with hepatocellular carcinoma(HCC). This paper reviews the research progress of SHH pathway and HCC.