Therapeutic strategy of targetingepigenetic crosstalk for EZH2-aberrant solid tumors

摘要

With the support by the National Natural Science Foundation of China and the Chinese Academy of Sciences,the team led by Geng MeiYu (耿美玉),Ding Jian and Tan MinJia at Shanghai Institute of Materia Medica (SIMM),Chinese Academy of Sciences revealed the mechanisms that essentially determine the therapeutic response to EZH2inhibitors and proposed therapeutic solutions for EZH2-aberrant solid tumors,which was published in Cell (2018,175(1).186-199)