Objective To explore the effects of pre-pregnancy prevention and intervention combined with comprehensive fetus protection treatments on re-pregnancy success rate of people with embryo damage history. Methods Excluded chromosome abnormality and other known correlated factors which may have effect on embryo development, 512 patients with embryo damage history were divided into two groups according to their willingness. Group A (n=199), without previous treatment, received only fetus protection after pregnancy, group B(n=313)received combined treatments before and after pregnancy, then the re-pregnancy success rate was compared in two groups. Results The success rate of re-pregnancy in group B was significantly higher than that in group A (χ2=108.296, P<0.05). Conclusion Pre-pregnancy prevention and intervention combined with comprehensive fetus protection treatments can effectively increase the successful rate of re-pregnancy for people with embryo damage history.%目的：探讨孕前预防干预与孕早期综合保胎治疗相结合对胚胎停育史患者再次妊娠成功率的影响。方法通过排除其中染色体异常和其他已知的可能影响胚胎发育的相关因素,筛查出512例有胚胎停育史患者,据患者意愿将其分为A、B两组, A组199例,不选择前期治疗,要求妊娠后直接保胎, B组313例,选择妊娠前后综合治疗,观察两组再次妊娠成功率。结果 B组再次妊娠成功率高于A组,差异具有统计学意义(χ2=108.296, P<0.05)。结论孕前预防干预与孕早期综合保胎综合治疗相结合,可有效提高胚胎停止发育史患者再次妊娠成功率。
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