目的 探究大剂量甲氨蝶呤子宫动脉灌注栓塞化疗术治疗胎盘植入产后出血的疗效.方法 43例接受大剂量子宫动脉灌注甲氨蝶呤化疗并栓塞术治疗胎盘植入产后出血的患者, 对其手术指标、治疗效果、术后并发症等进行分析.结果 43例接受治疗的患者全部顺利完成手术, 成功止血, 患者术后恢复好, 无严重不良反应, 远期并发症少.结论 大剂量甲氨蝶呤子宫动脉灌注栓塞化疗术治疗胎盘植入产后出血安全有效, 且能保留患者的生育功能, 有较高的临床实用价值.%To investigate curative effect of large dose of methotrexate by uterine arterial infusion embolization chemotherapy in the treatment of placenta implantation postpartum hemorrhage.Methods A total of 43 patients with placenta implantation postpartum hemorrhage received large dose of methotrexate by uterine arterial infusion embolization chemotherapy for treatment. Analysis was made on their operation indicators, curative effects, and postoperative complications.Results All the 43 cases received successful operation and hemostasis. They had good postoperative rehabilitation and no severe adverse reactions, with few short-term complications.Conclusion Implement of large dose of methotrexate by uterine arterial infusion embolization chemotherapy in the treatment of placenta implantation postpartum hemorrhage is safe and effective. This method can not only protect fertility function, but also contain highly clinical value for application.
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