探讨莫沙必利和黛力新治疗老年功能性消化不良的临床效果以及对患者心理状态的影响

摘要

目的：对莫沙必利和黛力新共同治疗老年功能性消化不良患者的临床效果以及对患者心理状态的影响情况进行分析与探讨。方法64例老年功能性消化不良患者，随机分为对照组和试验组，每组32例。对照组患者予以莫沙必利治疗；试验组患者予以莫沙必利和黛力新共同治疗。对比两组患者治疗前后的汉密顿焦虑量表(HAMA）、汉密顿抑郁量表(HAMD)的评分及临床治疗的效果情况。结果试验组患者的临床总有效率(96.88%)、HAMA评分(9.09±3.25)分、HAMD评分(8.03±0.81)分均明显优于对照组的临床总有效率(68.75%)、HAMA评分(15.49±3.42)分、HAMD评分(14.01±0.49)分，差异均有统计学意义(P<0.05)。结论对老年功能性消化不良的患者，予以莫沙必利和黛力新共同治疗的措施后，临床治疗的效果显著提升，老年患者的焦虑、抑郁、烦躁、紧张等心理状态也均有了显著改善，可推广使用。%Objective To analyze and investigate clinical effect by mosapride combined with deanxit in the treatment of senile functional dyspepsia and their influence on psychological states of patients.Methods A total of 64 senile functional dyspepsia patients were randomly divided into control group and experimental group, with 32 cases in each group. The control group received mosapride for treatment, and the experimental group received mosapride and deanxit for combined treatment. Comparisons were made on scores in Hamilton anxiety scale (HAMA) and Hamilton depression scale (HAMD), and clinical effects before and after treatment between the two groups.Results The experimental group had obviously better clinical total effective rate as 96.88%, HAMA score as (9.09±3.25) points, and HAMD score as (8.03±0.81) points than 68.75%, (15.49±3.42) points and (14.01±0.49) points of the control group. Their differences all had statistical significance (P<0.05). Conclusion Combined treatment by mosapride and deanxit for senile functional dyspepsia patients provides remarkable improvements in clinical effect and psychological states of anxiety, depression, dysphoria, and tension. This method can be promoted and applied.