Ⅰ类切口手术患者围手术期预防应用抗菌药物的合理性分析

摘要

Objective To explore intervention effect of antibacterial agents rationally applied in perioperative operation patients with type Ⅰ incision. Methods A total of 1000 type Ⅰ incision patients were divided into before intervention (January 2014~January 2015) and after intervention (February 2015~February 2016), with 500 cases in each stage. Reasonability of antibacterial agents application was analyzed before and after intervention. Results There were 324 cases (64.8%) of perioperative prophylactic application of antibacterial agents before intervention, with reasonable drug varieties as 232 cases (71.6%), reasonable drug timing as 271 cases (83.6%), reasonable drug course as 104 cases (32.1%), and mean antibacterial agents ues time as (3.25±3.45) d, which were all better than 198 cases (39.6%), 177 cases (89.4%), 179 cases (90.4%), 85 cases (42.9%) and (2.15±3.26) d before intervention, and differences had statistical significance (P<0.05). Conclusion Perioperative application of antibacterial agents is popular for patients with type Ⅰ incision in this hospital. The rate decreases after intervention, and drug use become more reasonable.%目的：探讨Ⅰ类切口手术患者围手术期合理预防应用抗菌药物的干预效果。方法1000例Ⅰ类切口手术患者，将其分为干预前(2014年1月~2015年1月)和干预后(2015年2月~2016年2月)，各500例。分析干预前后的抗菌药物使用的合理性。结果干预前围手术期预防性应用抗菌药物者324例(64.8%)，合理的用药品种232例(71.6%)，合理的用药时机271例(83.6%)，合理的用药疗程104例(32.1%)，平均使用抗菌药物时间为(3.25±3.45)d与干预后的198例(39.6%)、177例(89.4%)、179例(90.4%)、85例(42.9%)及(2.15±3.26)d 比较，差异有统计学意义(P<0.05)。结论该院Ⅰ类切口手术患者围手术期预防应用抗菌药物的使用情况较多，经干预措施后使用率降低，使患者用药更加的合理化。