降钙素原在外科感染性疾病中的临床应用价值

摘要

目的：探讨降钙素原(PCT)在外科感染性疾病中的临床应用价值。方法65例外科手术患者,根据出院诊断将其分为脓毒血症组(15例)、局部感染组(27例)、非感染对照组(23例)。比较入院当天的PCT差异。结果脓毒血症组及局部感染组PCT浓度[(15.62±12.17)、(4.39±3.52)ng/ml]均高于非感染对照组(0.45±0.16) ng/ml,差异均有统计学意义(P<0.05)；脓毒血症组高于局部感染组(P<0.05)。结论PCT 可作为外科判断是否存在细菌感染及感染严重程度的可靠指标,并对合理使用抗生素有重要的参考价值。%ObjectiveTo investigate clinical application value of procalcitonin (PCT) in surgical infectious diseases.MethodsA total of 65 patients, who received surgical operation, were divided by their discharge diagnosis into septicopyemia group (15 cases), local infection group (27 cases) and non-infection control group (23 cases). Comparison was made on difference of PCT between the groups.ResultsThe septicopyemia group had the local infection group had all higher PCT concentration[(15.62±12.17) and (4.39±3.52) ng/ml]than (0.45±0.16) ng/ml in the non-infection control group. Their differences all had statistical significance (P<0.05). The septicopyemia group also had higher concentration than the local infection group (P<0.05).ConclusionAsa creditable indicator, PCT can be taken in diagnosis of surgical bacterial infection and infection severity. It also contains important reference value for rational antibiotics use.