头孢菌素类抗生素的药理特性及临床应用分析

摘要

ObjectiveTo analyze pharmacological characteristics and clinical application of cephalosporins antibiotics.MethodsClinical data of 110 patients with antibiotics-related adverse reactions were retrospectively analyzed. Observation was made on adverse reactions and involved regions by cephalosporins antibiotics.ResultsThere were 45 cases with adverse reactions by cephalosporins antibiotics among 110 patients, accounting for 40.9%. Main involved regions included digestive system, nervous system, skin and appendages of skin.ConclusionCephalosporins antibiotics-induced adverse reactions mainly involve digestive system, nervous system, skin and appendages of skin. Therefore, understanding pharmacological characteristics and closely observing clinical symptom and vital signs can reduce incidence of adverse reactions and improve curative effects for patients.%目的：探索分析头孢菌素类抗生素的药理特性及临床应用。方法回顾性分析110例抗生素相关不良反应患者的临床资料，观察本组患者中由于头孢菌素类抗生素的应用而出现的不良反应的发生情况、累及部位等。结果110例患者中由于应用头孢菌素类抗生素出现不良反应者45例，占总体的40.9%，累及的部位主要包括消化系统、神经系统、皮肤、皮肤附件等。结论应用头孢菌素类抗生素后，患者出现的不良反应主要涉及消化系统、神经系统、皮肤、皮肤附件等部位，因此在临床用药时，需要掌握药理特性，严密观察患者的临床症状和体征情况，以降低不良反应发生率，提高患者的治疗效果。