目的：探讨使用酒精所致精神和行为障碍患者的脑电图变化及其与饮酒量、饮酒史和临床类型的关系。方法回顾性分析126例使用酒精所致精神和行为障碍患者的住院资料。结果126例患者中脑电图正常66例(正常组),异常60例(异常组),正常组饮酒量为125~800 g/d,平均饮酒量(295.2±94.6)g/d,异常组饮酒量为130~875 g/d,平均饮酒量(299.0±94.0)g/d,两组比较差异无统计学意义(P>0.05)。饮酒史正常组为2~36年,平均饮酒史(17.2±9.02)年,异常组3~45年,平均饮酒史(21.0±9.6)年,两组比较差异无统计学意义(P>0.05)；两组震颤谵妄、遗忘综合征发生情况比较差异有统计学意义(P<0.05)。结论使用酒精所致精神和行为障碍对脑功能影响及对脑组织的损害是弥漫性的,脑电图异常与饮酒量及饮酒史无关,与临床表现类型有关。%Objective To investigate change of electroencephalogram in patients with ethyl alcohol-induced mental and behavioural disorders, and its relationship with drinking amount, history of alcohol intake and clinical classification.Methods Hospitalization data of 126 patients with ethyl alcohol-induced mental and behavioural disorders were retrospectively analyzed.Results Among the 126 patients, 66 cases had normal electroencephalogram (normal group) and 60 cases had abnormal electroencephalogram (abnormal group). The normal group had drinking amount as 125~800 g/d, with the average amount as (295.2±94.6) g/d, and the abnormal group had drinking amount as 130~875 g/d, with the average amount as (299.0±94.0) g/d. There was no statistical significance of the difference between the two groups (P>0.05). The normal group had history of alcohol intake as 2~36 years, with the average time as (17.2±9.02) years, and the abnormal group had history of alcohol intake as 3~45 years, with the average time as (21.0±9.6) years. The difference between the two groups had no statistical significance (P>0.05). The difference of occurrence of delirium tremens and amnestic syndrome between the two groups had statistical significance (P<0.05).Conclusion Ethyl alcohol-induced mental and behavioural disorders shows diffuse damage to brain function and tissue. Electroencephalogram is related with classification of clinical manifestations, while not with drinking amount and history of alcohol intake.
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