目的:探讨黄芪改善心功能的可能机制。方法:在42例慢性心力衰竭患者中,观察基础抗心衰治疗加用黄芪治疗对心功能及肿瘤坏死因子的影响。结果:与基础治疗组相比较,加用黄芪组心功能改善更显著,而且血清TNF-α水平明显降低。结论:黄芪可能具有降低肿瘤坏死因子的作用,有助于改善心功能。%OBJECTIVE:To explore the possible mechanism of astragalus in improving cardiac function.METHODS:To observe the effects of astragalus,added to basic anti-heart-failure therapy,on cardiac function and TNF in 45 cases of thronic heart failure.RESULTS:In comparison with basic therapy group,the improvement of cardiac function was more obvious and the level of serum TNF-α was lower in astragalus group.CONCLUSION:Astragalus probably has the action of decreasing TNF resulting in improvement of cardiac function.
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