抗耐甲氧西林金黄色葡萄球菌抗菌药物的药学干预评估

摘要

OBJECTIVE: To evaluate the effect of clinical pharmacists intervening in use of anti-MRSA antibiotics in our hospital, METHODS: By using retrospective method, 160 medical records of inpatients in our hospital during Jan. to Mar. 2011 (before intervention) and Jul. to Sept. 2011 (after intervention) were analyzed statistically. RESULTS: After pharmaceutical systemic and individual interference, rational use of anti-MRSA antibiotics was improved in our hospital. The ratio of irrational drug use had declined from 36.88% to 23.13%. CONCLUSION: Clinical pharmacists' interference of anti-MRSA antibiotics has obtained initial success in our hospital. We should use the drugs rationally to avoid uncontrollable drug resistance.%目的:评价我院临床药师干预抗耐甲氧西林金黄色葡萄球菌(MRSA)抗菌药物应用的效果.方法:采用回顾性方法,选取我院2011年1-3月(干预前)和7-9月(干预后)应用抗MRSA抗菌药物的患者病历各160份进行统计、分析.结果:经过药学方面的系统干预和个体干预,我院抗MRSA抗菌药物的用药合理性得到了较大提高,用药不合理比例由干预前的36.88％下降到了干预后的23.13％.结论:我院临床药师在短期内干预抗MRSA抗菌药物的应用已初见成效；临床需规范应用抗MRSA类抗菌药物,以免出现难以控制的耐药局面.