ASSESSMENT OF RESISTANCE DEVELOPMENT TO VALNEMULIN IN ENTEROCOCCUS FAECIUM AND ASSOCIATED CROSS RESISTANCE TO SEVEN OTHER ANTIMICROBIALS

摘要

The association of antimicrobial resistance development by human pathogens due to the use of antimicrobials in food animals is a highly controversial issue globally. The use of antimicrobials in food animals has been incriminated by direct exposure tofoodborne pathogens (ie. Salmonella), as well as indirectly through commensul organisms such as Enterococcus spp.This study was carried out to assess whether changes in the valnemulin susceptibility of E. faecium strains might occur following repeated sub-culture in the presence of sub-inhibitory concentrations of valnemulin hydrochloride.