目的:探讨在疾病诊断相关组预付费制度(DRGs-PPS)下的临床药师参与股骨颈骨折临床路径的实施效果,为促进临床合理用药提供参考.方法:收集我院进入临床路径的股骨颈骨折患者作为研究对象.2015年1-12月的患者为对照组,入径52例,完成路径41例;2016年1-12月的患者为观察组,入径58例,完成路径46例.临床药师参与观察组患者的临床路径实施,对临床用药进行技术干预和行政干预,对照组未进行干预.观察两组患者住院时间、住院费用、药品费用及不良反应情况,并比较两组患者预防用抗菌药物、镇痛药、辅助用药、抗骨质疏松药、抗凝药等5类药物的合理性.结果:临床药师参与观察组临床路径实施后,两组患者住院时间和不良反应发生率比较,差异均无统计学意义(P>0.05);观察组患者的住院费用、药品费用显著低于对照组,差异均有统计学意义(P0.05); hospitalization cost and drug cost of observation group were significantly lower than those of control group,with statistical significance(P<0.05). Medication time and cost of antibiotics for prophylactic use,cost of analgesic drugs,medication time of adjuvant drugs in observation group were significantly shorter/lower than control group;type of anti-osteoporosis drugs was significantly more than control group,with statistical significance(P<0.05). CONCLUSIONS:Under DRGs-PPS,the participation of linical pharmacists participating in the implementation of femoral neck fracture clinical pathway can play an important role in regulating the clinical rational use of 5 kinds of drugs and ensuring the safety,effectiveness and econom-ics of drug use.
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