剖宫产术前输注醋酸钠钾镁钙葡萄糖注射液对新生儿血气、血糖、乳酸及电解质的影响

摘要

目的：观察剖宫产术前应用醋酸钠钾镁钙葡萄糖注射液对新生儿血气、血糖、乳酸及电解质的影响。方法选取2013年5月至12月需行剖宫产手术患者60例，依据分层随机分组法将患者分为治疗组及对照组，每组30例。对照组给予常规术前准备并进行剖宫产术；治疗组在对照组处理的基础上于术前加用醋酸钠钾镁钙葡萄糖注射液进行治疗。观察比较两组孕产妇手术前后血糖、游离脂肪酸、酮体变化以及用药不良反应情况，检测两组新生儿血气分析、电解质、血糖、乳酸及Apgar评分情况。结果术前两组孕产妇空腹血糖（FBG）、游离脂肪酸（NEFA）及酮体（KB）比较，差异无统计学意义（ P>0.05）。术后治疗组孕产妇FBG为（6.75±1.71）mmol/L，明显高于对照组的（5.86±1.62）mmol/L，孕产妇 NEFA 为（0.57±0.18）mmol/L，KB 为（0.14±0.06）mmol/L，均分别低于对照组的（0.71±0.26）mmol/L和（0.19±0.09）mmol/L（ P0.05）。结论剖宫产术前应用醋酸钠钾镁钙葡萄糖注射液，可显著改善孕产妇能量物质代谢情况及新生儿血气、电解质状况，并可提高新生儿Apgar评分。%Objective To observe the effect of Sodium Acetate Potassium Magnesium Calcium Glucose Injection on neonatal blood gas, blood glucose, lactate and electrolytes before cesarean section. Methods 60 pregnant woman requiring cesarean section in our hospital from May to December 2013 were divided into the treatment group and the control group according to the stratified randomized method, 30 cases in each group. The control group was given the routine preoperative preparation and performed cesarean section;while the treatment group was added with Sodium Acetate Potassium Magnesium Calcium Glucose Injection before operation on the basis of the control group treatment;the changes of blood glucose, free fatty acids, ketone bodies ( KB ) and adverse drug reactions before and after operation were observed and compared between the two groups; the blood gas analysis, electrolytes, blood glucose, lactate and Apgar scores of neonates after cesarean section were detected in the two groups. Results The fasting blood glucose ( FBG ) , free fatty acid ( NEFA ) and KB before operation had no statistical differences between the two groups ( P>0. 05 ); FBG after operation was ( 6. 75 ± 1. 71 ) mmol/L in the treatment group, which was higher than ( 5. 86 ± 1. 62 ) mmol/L in the control group, NEFA and KB were ( 0. 57 ± 0. 18 ) mmol/L and ( 0. 14 ± 0. 06 ) mmol/L in the treatment group, which were lower than ( 0. 71 ± 0. 26 ) mmol/L and ( 0. 19 ± 0. 09 ) mmol/L in the control group, the differences were statistically significant ( P 0. 05 ) . Conclusion Using Sodium Acetate Potassium Magnesium Calcium Glucose Injection before cesarean section can significantly improve the energy substance metabolism in pregnant and lying-in woman and the condition of neonatal blood gas and electrolytes , and can improve the Apgar scores of neonates.