目的 探讨多烯磷脂酰胆碱联合腺苷蛋氨酸对酒精性肝硬化患者肝纤维化的影响.方法 选取医院2014年1月至2015年4月收治的酒精性肝硬化患者72例,随机分为观察组及对照组,各36例.对照组患者给予护肝、支持及对症基础治疗,观察组在对照组基础上加用多烯磷脂酰胆碱和腺苷蛋氨酸.结果 治疗30 d后,观察组总有效率为83. 33%,高于对照组的69. 44%( P0. 05).结论 多烯磷脂酰胆碱联合腺苷蛋氨酸治疗酒精性肝硬化,能显著提高临床疗效,改善肝功能,同时抑制和逆转肝纤维化的发生,安全性好,值得临床推广.%Objective To investigate the efficacy of polyene phosphatidyl choline combined with adenosine methionine effects on liver fibrosis of patients with alcoholic liver cirrhosis. Methods 72 cases of patients with alcoholic liver cirrhosis from January 2014 to April 2015 were selected and randomly divided into observation group and control group, 36 cases in each group. The control group was given polyene phosphatidyl choline, and the treatment group was given polyene phosphatidyl choline and adenosine methionine. Results After treatment, the total effective rate of the observation group was 83. 33%, which was significantly higher than 69. 44% of the control group ( P 0. 05 ) . Conclusion The polyene phosphatidyl choline combined with adenosine methionine in treating alcoholic cirrhosis of the liver can significantly improve the clinical efficacy and liver function, inhibit or reverse the occurrence of liver fibrosis with no adverse reactions, which is worthy of clini-cal and promotion.
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